One of the reasons people are still becoming infect with HIV is the computer virus comes in different strain , and it is operose to design a single vaccine that do work against all of them . However , a vaccine that has already produced encouraging results against the HIV strains in Thailand has now been found to bring about an even crowing immune response to the most vulgar forms in South Africa , raising hopes it could be effective in one of the most AIDS - hit countries .
As therapy have change state HIV contagion from a death prison term to a manageable condition for those who can afford them , the menace of AIDS has fleet from the thinker of moneyed commonwealth . Yet globally HIV is still one of the turgid Orcinus orca , takingalmost a millionlives a twelvemonth , and forcing many others to spend more than they can afford on drugs to keep themselves alert . Only a vaccinum will change this .
Several observational edition have been tried , with varying levels of success . None are ready for widespread use , but RV144 , whichreduced infection ratesby 31 percent compared to a placebo in Thai trials is view as a promising stepping pit .
HIV has mutate in its travel , and different strains are prevailing in different regions . Those coarse in Thailand and South Africa , jazz as clade B and C respectively , are importantly different . Dr Glenda Grayof Witwatersrand University gave a 100 HIV negative South Africans the RV144 vaccine as part of a phase1b test and quiz for anti - HIV antibodies and T cell responses .
The resistant responses of the South Africans were really more or less stronger against clade C HIV computer virus than the Thai reply against clade B. For example , the IgB antibody produced by people given the vaccinum bonded more strongly in test tubes to South African version of the computer virus than to Thai ones . InScience Translational Medicine , Gray mention the stronger responses occurred irrespective of the age or sex activity of those kick in the vaccinum .
This suggests that , if a similar test was run among South Africans , the tribute against HIV infection would be at least as secure .
In some portion , a vaccinum that reduces infections by less than a third might still be deserving making widely available . Not only would it hold enter the lives of those it protected , but it would supply weakherd immunityfor everyone else , potentially cause pace of transmittal to corkscrew down not up .
However , things are more knotty with HIV , because there are concerns hoi polloi who are vaccinated may be more probable to engage in risky behavior , such as failing to utilize condoms . Consequently , RV144 will call for to be improve before it can be wide deploy , on any continent . Nevertheless , Gray ’s work suggests the goal is getting close .
