Scientists from the University of Aberdeen say that a drug used to treat breast cancer and diabetes can also “ melt away ” fat inside artery .
In studies on black eye , the scientist found that a single venereal disease of the drug Trodusquemine could repeal the effects of coronary artery disease , a disease that can stimulate legion heart problem . The research is published in the journalClinical Science .
“ Trodusquemine has already been trialed for discussion of diabetes and breast Cancer the Crab but this is the first time it has been used in models of coronary artery disease , ” said Professor Mirela Delibegovic , lead author of the study , in astatement .
“ These have only been screen at pre - clinical tier , in computer mouse , so far but the results were quite impressive and read that just a unmarried Elvis of this drug seemed to totally reverse the effects of atherosclerosis . ”
Everyone has some level ofatherosclerosis , which can cause nerve attacks and stroking . It can be a enceinte problem for people who are overweight or who have underlie cardiovascular conditions .
It get the ramp up - up of fatty material inside artery . Over metre this cloth can grow big , until the arteria become narrow and prevent enough blood passing through .
In these exam , the mice treat with just a single dose of Trodusquemine had less roly-poly memorial tablet over time , leading to the claim that it had fade off fat . The drug stop an enzyme called PTP1B , which is something that ’s more prevalent in people with obesity or diabetes .
The drug was also chance to stimulate a protein called AMPK , which mimic exercise and slenderize chronic kindling . This is the first time the drug has been shown to help oneself forbid cardiovascular disease .
The inquiry has only been conducted in mouse so far , but the scientists trust to quiz it in human patients in hereafter .
“ Trodusquemine is in early clinical trial for the treatment of diabetes , ” said Professor Jeremy Pearson , Associate Medical Director at the British Heart Foundation , in the statement .
“ This study shows it can also limit the soma - up of fatty atherosclerotic plaques in mice . If we see the same effect in patients , the drug may prove even more useful than currently hoped for . ”